RAR-Related Orphan Receptor C (RORC) (N-Term) Peptide
RORC
Reactivity: Mouse
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN983134
Quick Overview for RAR-Related Orphan Receptor C (RORC) (N-Term) Peptide (ABIN983134)
Target
RORC
(RAR-Related Orphan Receptor C (RORC))
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Sequence
- VKFGRMSKKQ RDSLHAEVQK QLQQQQQQEQ VAKTPPAGSR GADTLTYTLG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Rorc Antibody(ARP37127_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RORC (RAR-Related Orphan Receptor C (RORC))
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Background
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Rorc is an orphan nuclear receptor. Isoform 2 negatively regulates expression of TNFSF6/FASL and IL2 production in T-cells. It also binds to the TEA promoter and may participate in the regulation of DNA accessibility in the TCR-Jalpha locus.
Alias Symbols: Nr1f3, RORgamma, TOR, Thor
Protein Size: 516 -
Molecular Weight
- 58 kDa
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Gene ID
- 19885
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NCBI Accession
- NM_011281, NP_035411
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UniProt
- P51450
Target
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